Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17084528 | 0.86 | KMT2A (0.61) | KMT2AMEN1SMN1; SMN2RXFP1TDP1 | |
| SCHEMBL7330954 | 0.82 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2MAPTCYP2C9 | |
| SCHEMBL7338994 | 0.81 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2PRSS1ACR | |
| SCHEMBL17084527 | 0.81 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2RXFP1TDP1 | |
| SCHEMBL7331661 | 0.81 | ALDH1A1 (0.57) | KMT2AMEN1SMN1; SMN2MAPTCYP2C9 | |
| SCHEMBL17084524 | 0.81 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2RXFP1TDP1 | |
| SCHEMBL7339076 | 0.80 | SMN1; SMN2 (0.60) | KMT2AMEN1SMN1; SMN2PRSS1ACR | |
| SCHEMBL7341015 | 0.80 | TSHR (0.58) | KMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL7339865 | 0.80 | KMT2A (0.55) | KMT2AMEN1SMN1; SMN2RXFP1MAPT | |
| SCHEMBL7339630 | 0.80 | MEN1 (0.51) | KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475531-B1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | ASAHI CHEMICAL IND (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0475531-A1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-03-18 | — | — | EP | disclosed |