Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735543 | 0.86 | TYMP (0.64) | TYMPPRMT5WDR77ADORA1 | |
| SCHEMBL17911711 | 0.85 | TYMP (0.45) | TYMP | |
| SCHEMBL18486223 | 0.84 | TYMP (0.43) | TYMPADORA1 | |
| SCHEMBL24191239 | 0.84 | ADORA1 (0.49) | TYMPADORA1 | |
| SCHEMBL18486221 | 0.84 | TYMP (0.54) | TYMPADORA1 | |
| SCHEMBL18486346 | 0.83 | TYMP (0.44) | TYMP | |
| SCHEMBL9773298 | 0.82 | TYMP (0.42) | TYMPADORA1 | |
| SCHEMBL18486202 | 0.81 | TYMP (0.46) | TYMP | |
| SCHEMBL12856900 | 0.79 | NPC1 (0.52) | — | |
| SCHEMBL2991173 | 0.79 | NPC1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138330-B2 | Solid phase synthesis via deblocking immobilized nucleoside, then coupling acyl protected nucleoside phosphoramidite | SIGMA-ALDRICH CO. LLC (US) | 2012-03-20 | — | — | US | disclosed |