Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327346 | 0.92 | ITGB3 (0.32) | — | |
| SCHEMBL7332680 | 0.91 | ITGB3 (0.34) | MEN1KMT2ATP53 | |
| Trifluoroacetic Acid SCHEMBL7334105 | 0.91 | MEN1 (0.36) | MEN1KMT2ATP53 | |
| SCHEMBL7331919 | 0.90 | PTGDR2 (0.31) | MEN1KMT2ATP53 | |
| SCHEMBL7319156 | 0.90 | MEN1 (0.33) | MEN1KMT2ATP53 | |
| SCHEMBL7330877 | 0.87 | ITGB3 (0.32) | MEN1KMT2ATP53 | |
| SCHEMBL7326326 | 0.87 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL7325995 | 0.85 | — | — | |
| Trifluoroacetic Acid SCHEMBL7327342 | 0.85 | ITGB3 (0.37) | — | |
| SCHEMBL8842584 | 0.84 | MEN1 (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663166-A | ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING | GENENTECH, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0610334-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII b?III a? RECEPTOR. | GENENTECH INC (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993008174-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPIIbIIIa RECEPTOR | GENENTECH, INC. (US) | 1993-04-29 | — | — | WO | disclosed |