Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 4/20 | 0.66 |
| ▸ | PLAU | P00749 | 4/20 | 0.66 |
| ▸ | CHEK2 | O96017 | 9/20 | 0.65 |
| ▸ | MPL | P40238 | 1/20 | 0.62 |
| ▸ | RARB | P10826 | 3/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334119 | 0.91 | RARB (0.62) | PLGPLAUCHEK2MPLRARB | |
| SCHEMBL7333360 | 0.90 | PLG (0.62) | PLGPLAUCHEK2HDAC6 | |
| SCHEMBL1663391 | 0.89 | CHEK2 (0.80) | PLGPLAUCHEK2NR4A2HDAC6 | |
| SCHEMBL13305839 | 0.85 | PLG (0.60) | PLGPLAUCHEK2HDAC6 | |
| SCHEMBL27573983 | 0.85 | CHEK2 (0.69) | PLGPLAUCHEK2MPLNR4A2 | |
| SCHEMBL20982527 | 0.84 | CHEK2 (0.78) | PLGPLAUCHEK2NR4A2HDAC6 | |
| SCHEMBL1662761 | 0.82 | CHEK2 (0.93) | CHEK2NR4A2TP53TSHR | |
| SCHEMBL7333347 | 0.82 | SMN1; SMN2 (0.54) | PLGPLAUCHEK2HDAC6TP53 | |
| SCHEMBL20982644 | 0.82 | NR4A2 (0.86) | CHEK2NR4A2HDAC6 | |
| SCHEMBL18229635 | 0.81 | HDAC6 (0.80) | PLGPLAUCHEK2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-B1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-12-11 | — | — | EP | disclosed |
| US-6265536-B1 | MICROBIOCIDE AND FUNGICIDE WHICH IS INHIBITOR OF BETA-1,3-GLUCAN SYNTHASE; TREATMENT OF PNEUMOCYSTIS CARINII INFECTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6107458-A | FUNGICIDE WHICH IS BETA-1,3-GLYCAN SYNTHASE INHIBITOR; FOR PROPHYLAXIS AND TREATMENT OF PNEUMOCYSTIS CARINII INFECTIONS LIKE PNEUMONIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-22 | — | — | US | disclosed |
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996011210-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-18 | — | — | WO | disclosed |