Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | RHEB | Q15382 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333360 | 0.92 | PLG (0.62) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7334119 | 0.90 | RARB (0.62) | PLGPLAUCHEK2TP53 | |
| SCHEMBL13305839 | 0.84 | PLG (0.60) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29906102 | 0.83 | KDM4E (0.75) | SMN1; SMN2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL25318263 | 0.83 | KDM4E (0.75) | SMN1; SMN2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL465519 | 0.83 | SIRT2 (0.62) | HDAC6PLGPLAUCHEK2MAPT | |
| SCHEMBL7334131 | 0.82 | PLG (0.66) | HDAC6PLGPLAUCHEK2TP53 | |
| SCHEMBL8768386 | 0.80 | ATM (0.56) | SMN1; SMN2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL14381943 | 0.80 | KDM4E (0.70) | SMN1; SMN2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL6178276 | 0.79 | KDM4E (0.59) | SMN1; SMN2KDM4ENPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-B1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-12-11 | — | — | EP | disclosed |
| US-6265536-B1 | MICROBIOCIDE AND FUNGICIDE WHICH IS INHIBITOR OF BETA-1,3-GLUCAN SYNTHASE; TREATMENT OF PNEUMOCYSTIS CARINII INFECTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6107458-A | FUNGICIDE WHICH IS BETA-1,3-GLYCAN SYNTHASE INHIBITOR; FOR PROPHYLAXIS AND TREATMENT OF PNEUMOCYSTIS CARINII INFECTIONS LIKE PNEUMONIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-22 | — | — | US | disclosed |
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996011210-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-18 | — | — | WO | disclosed |