Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1532728 | 0.83 | CA12 (0.42) | PTPN1L3MBTL1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL16479216 | 0.78 | SCN8A (0.42) | PTPN1L3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL2522911 | 0.76 | ALDH1A1 (0.47) | PTPN1L3MBTL1GLATSHRKMT2A | |
| SCHEMBL14612800 | 0.73 | SMN1; SMN2 (0.53) | PTPN1L3MBTL1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL1989131 | 0.72 | ALDH1A1 (0.62) | TSHRSMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL147753 | 0.72 | SCN4A (0.54) | GLATSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6259721 | 0.71 | PPARA (0.48) | L3MBTL1TSHRSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL16958650 | 0.70 | CHRM2 (0.43) | PTPN1L3MBTL1TSHRKDM4ETDP1 | |
| SCHEMBL1148349 | 0.70 | NQO1 (0.52) | TSHRKMT2AALDH1A1TDP1CYP3A4 | |
| SCHEMBL23871139 | 0.70 | PPARA (0.55) | L3MBTL1SMN1; SMN2KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526708-B1 | Sulfonamide, preparation and use thereof as medicine and intermediate | HOFFMANN LA ROCHE (CH) | 2000-10-18 | — | — | EP | disclosed |
| EP-0526708-A1 | Sulfonamide, preparation and use thereof as medicine and intermediate | F. HOFFMANN-LA ROCHE AG (CH) | 1993-02-10 | — | — | EP | disclosed |