Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294981 | 0.90 | SIGMAR1 (0.77) | SIGMAR1 | |
| SCHEMBL13462730 | 0.87 | F10 (0.54) | — | |
| SCHEMBL466899 | 0.86 | SIGMAR1 (0.68) | SIGMAR1 | |
| SCHEMBL7294940 | 0.85 | SIGMAR1 (0.70) | SIGMAR1 | |
| SCHEMBL7295004 | 0.84 | SIGMAR1 (0.69) | SIGMAR1 | |
| SCHEMBL13439734 | 0.84 | F10 (0.52) | — | |
| SCHEMBL9737745 | 0.79 | SLC6A2 (0.63) | SIGMAR1 | |
| SCHEMBL29960102 | 0.78 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL28514024 | 0.78 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL7362469 | 0.77 | SIGMAR1 (0.71) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449187-A2 | Piperidin ether derivatives as psychotropic drugs or plant fungicides | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-10-02 | — | — | EP | claimed |
| US-5169855-A | PIPERIDINE ETHER DERIVATIVES AS PSYCHOTROPIC DRUGS OR PLANT FUNGICIDES | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0449187-A2 | Piperidin ether derivatives as psychotropic drugs or plant fungicides | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-10-02 | — | — | EP | disclosed |