Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335649 | 1.00 | GABRA1 (0.39) | GABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL7328033 | 0.89 | GABRA1 (0.40) | GABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL7328024 | 0.89 | GABRA1 (0.40) | GABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL7328853 | 0.88 | GABRA1 (0.52) | GABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL7362181 | 0.88 | GABRA1 (0.52) | GABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL7328859 | 0.88 | GABRA1 (0.52) | GABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL7328384 | 0.88 | GABRA1 (0.40) | GABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL7329687 | 0.88 | GABRA1 (0.52) | GABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL8600763 | 0.86 | MAPT (0.41) | — | |
| SCHEMBL8600770 | 0.86 | MAPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833638-B1 | USE OF IMIDAZO 1,5-a]QUINOLONES AS NEUROPROTECTIVE AGENTS | UPJOHN CO (US) | 2001-11-21 | — | — | EP | claimed |
| US-5935970-A | Use of imidazo 1,5-a!quinolones as neuroprotective agents | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-10 | — | — | US | claimed |
| EP-0729469-B1 | IMIDAZO [1,5-a]QUINOLINES FOR TREATMENT OF ANXIETY AND SLEEP DISORDERS | UPJOHN CO (US) | 1998-09-23 | — | — | EP | claimed |
| US-RE35840-E | Imidazo 1,5-a!quinolines for treatment of anxiety and sleep disorders | PHARMACIA & UPJOHN COMPANY (US) | 1998-07-07 | — | — | US | claimed |
| EP-0833638-A1 | USE OF IMIDAZO 1,5-a]QUINOLONES AS NEUROPROTECTIVE AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-08 | — | — | EP | claimed |
| US-5594140-A | Imidazo[1,5-A]quinolines for treatment of anxiety and sleep disorders | THE UPJOHN COMPANY (US) | 1997-01-14 | — | — | US | claimed |
| WO-1997000074-A1 | USE OF IMIDAZO[1,5-a]QUINOLONES AS NEUROPROTECTIVE AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1997-01-03 | — | — | WO | claimed |
| EP-0729469-A1 | IMIDAZO [1,5-a]QUINOLINES FOR TREATMENT OF ANXIETY AND SLEEP DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 1996-09-04 | — | — | EP | claimed |
| WO-1995014020-A1 | IMIDAZO[1,5-a]QUINOLINES FOR TREATMENT OF ANXIETY AND SLEEP DISORDERS | THE UPJOHN COMPANY (US) | 1995-05-26 | — | — | WO | claimed |