Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 11/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.49 |
| ▸ | OXTR | P30559 | 1/20 | 0.49 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059603 | 0.92 | AVPR2 (0.51) | AVPR2AVPR1AOXTRAVPR1BCHRNB2 | |
| SCHEMBL7319146 | 0.89 | AVPR2 (0.48) | AVPR2AVPR1AOXTRAVPR1BCHRNB2 | |
| SCHEMBL7333632 | 0.89 | AVPR2 (0.64) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL7337329 | 0.85 | AVPR2 (0.46) | AVPR2AVPR1A | |
| SCHEMBL7335574 | 0.84 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL7339550 | 0.83 | AVPR1A (0.51) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL7337254 | 0.81 | AVPR2 (0.52) | AVPR2AVPR1AOXTR | |
| SCHEMBL5945608 | 0.80 | AVPR2 (0.49) | AVPR2AVPR1AOXTRAVPR1BCHRNB2 | |
| SCHEMBL7342518 | 0.80 | AVPR2 (0.80) | AVPR2AVPR1A | |
| SCHEMBL5237135 | 0.79 | AVPR2 (0.54) | AVPR2AVPR1AOXTRAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |