Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 7/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.52 |
| ▸ | OXTR | P30559 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820724 | 0.89 | AVPR2 (0.52) | AVPR2AVPR1AHPGDALDH1A1RAB9A | |
| SCHEMBL7333632 | 0.85 | AVPR2 (0.64) | AVPR2AVPR1AOXTR | |
| SCHEMBL7335693 | 0.81 | AVPR2 (0.53) | AVPR2AVPR1AOXTR | |
| SCHEMBL7332888 | 0.80 | AVPR2 (0.65) | AVPR2AVPR1AOXTRHPGDALDH1A1 | |
| SCHEMBL8820600 | 0.75 | AVPR2 (0.53) | AVPR2RAB9ASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL7342518 | 0.74 | AVPR2 (0.80) | AVPR2AVPR1A | |
| SCHEMBL7313684 | 0.73 | AVPR2 (0.79) | AVPR2AVPR1AOXTR | |
| SCHEMBL9059603 | 0.73 | AVPR2 (0.51) | AVPR2AVPR1AOXTR | |
| SCHEMBL5237135 | 0.73 | AVPR2 (0.54) | AVPR2AVPR1AOXTR | |
| SCHEMBL2486302 | 0.73 | HPGD (0.50) | AVPR2AVPR1AHPGDALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |