SCHEMBL733614

SCHEMBL733614

NCCc1cccc2c(N)cccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.56
ALDH1A1 P00352 2/20 0.56
HPGD P15428 2/20 0.56
TSHR P16473 2/20 0.56
HSD17B10 Q99714 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
TAAR1 Q96RJ0 9/20 0.45
NR4A2 P43354 1/20 0.45
KEAP1 Q14145 1/20 0.43
MPO P05164 2/20 0.42
SLC6A4 P31645 1/20 0.42
HTR2A P28223 4/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2A6 P11509 1/20 0.41
NFKB1 P19838 1/20 0.41
HTR1D P28221 1/20 0.41
HTR1B P28222 1/20 0.41
HTR2C P28335 1/20 0.41
HTR7 P34969 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29592386 1.00 CYP3A4 (0.56) CYP3A4ALDH1A1HPGDTSHRHSD17B10
SCHEMBL6563339 0.89 TAAR1 (0.54) CYP3A4TAAR1MPOSLC6A4HTR2A
SCHEMBL13900823 0.88 ALDH1A1 (0.52) CYP3A4ALDH1A1HPGDTSHRHSD17B10
SCHEMBL13973214 0.87 TAAR1 (0.46) CYP3A4ALDH1A1HPGDTSHRHSD17B10
SCHEMBL13900822 0.82 ALDH1A1 (0.62) CYP3A4ALDH1A1HPGDTSHRHSD17B10
SCHEMBL22256360 0.81 ALDH1A1 (0.54) CYP3A4ALDH1A1HPGDTSHRHSD17B10
SCHEMBL9875092 0.79 ALDH1A1 (0.65) CYP3A4ALDH1A1HPGDTSHRHSD17B10
SCHEMBL17537729 0.79 TAAR1 (0.54) CYP3A4TAAR1MPOSLC6A4HTR2A
SCHEMBL9694974 0.78 TAAR1 (0.61) CYP3A4TAAR1MPOSLC6A4HTR2A
SCHEMBL28831361 0.77 ALDH1A1 (0.62) CYP3A4ALDH1A1HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9624555-B2 Sequences and methods for detecting influenza A and influenza B virus BECTON, DICKINSON AND COMPANY (US) 2017-04-18 US claimed
US-20100273156-A1 SEQUENCES AND METHODS FOR DETECTING INFLUENZA A AND INFLUENZA B VIRUS BECTON, DICKINSON AND COMPANY (US) 2010-10-28 US claimed
EP-2152871-A1 SEQUENCES AND METHODS FOR DETECTING INFLUENZA A AND INFLUENZA B VIRUS Becton, Dickinson & Company (US) 2010-02-17 EP claimed
WO-2008150998-A1 SEQUENCES AND METHODS FOR DETECTING INFLUENZA A AND INFLUENZA B VIRUS BECTON, DICKINSON AND COMPANY (US) 2008-12-11 WO claimed
CN-108026575-B Method for amplifying nucleic acid sequence 哈佛学院董事及会员团体 2022-08-19 CN disclosed
US-20210285038-A1 Methods of Whole Genome Digital Amplification PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-09-16 US disclosed
CN-108479872-B Integrated microfluidic systems, methods and kits for performing assays 基纽拜奥股份有限公司 2021-02-12 CN disclosed
US-10894980-B2 Methods of amplifying nucleic acid sequences mediated by transposase/transposon DNA complexes PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-01-19 US disclosed
EP-3325665-B1 METHODS OF AMPLIFYING NUCLEIC ACID SEQUENCES HARVARD COLLEGE (US) 2020-09-02 EP disclosed
US-20190002967-A1 Methods of Amplifying Nucleic Acid Sequences PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2019-01-03 US disclosed
EP-3325665-A1 METHODS OF AMPLIFYING NUCLEIC ACID SEQUENCES President and Fellows of Harvard College (US) 2018-05-30 EP disclosed
US-9976190-B2 Gardnerella vaginalis assay BECTON, DICKINSON AND COMPANY (US) 2018-05-22 US disclosed
US-5958700-A HYBRIDIZING OLIGONUCLEOTIDE HAVING BASE-PAIRED SECONDARY STRUCTURE AND LINKED QUENCHED FLUORESCENT DYES, SYNTHESIZING COMPLEMENTARY STRAND BY PRIMER EXTENSION CAUSING LINEARIZATION OF STRUCTURE AND CHANGING FLUORESCENCE BECTON, DICKINSON AND COMPANY (US) 1999-09-28 US disclosed
US-5935791-A HYBRIDIZING TO TARGET NUCLEIC ACID A DETECTOR NUCLEIC ACID OF HYBRIDIZED OLIGONUCLEOTIDES LINKED TO DYES, EXTENDING TARGET SEQUENCE ON FIRST OLIGONUCLEOTIDE DISPLACING SECOND OLIGONUCLEOTIDE, DETECTING CHANGE IN FLUORESCENCE BECTON, DICKINSON AND COMPANY (US) 1999-08-10 US disclosed
US-5928869-A USING A OLIGONUCLEOTIDE DETECTOR BECTON, DICKINSON AND COMPANY 1999-07-27 US disclosed
EP-0909823-A2 Detection of nucleic acids by fluorescence quenching Becton, Dickinson and Company (US) 1999-04-21 EP disclosed
US-5888739-A FLUORESCENCE ANALYSIS BECTON, DICKINSON AND COMPANY (US) 1999-03-30 US disclosed
EP-0881302-A2 Detection of nucleic acids by fluorescence quenching Becton, Dickinson and Company (US) 1998-12-02 EP disclosed
EP-0826780-A1 Detection of nucleic acids using G-quartets Becton, Dickinson and Company (US) 1998-03-04 EP disclosed
US-5691145-A OLIGONUCLEOTIDE LABELLED WITH DONOR FLUOROPHORE AND ACCEPTOR DYE; DETECTING CHANGE IN FLUORESCENCE BECTON, DICKINSON AND COMPANY (US) 1997-11-25 US disclosed