Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336245 | 1.00 | TRPA1 (0.35) | TRPA1 | |
| SCHEMBL6369140 | 0.78 | — | — | |
| SCHEMBL6369137 | 0.78 | — | — | |
| SCHEMBL6369143 | 0.78 | — | — | |
| SCHEMBL6369008 | 0.78 | — | — | |
| SCHEMBL6369014 | 0.78 | — | — | |
| SCHEMBL6369005 | 0.78 | — | — | |
| SCHEMBL5050147 | 0.71 | TRPA1 (0.58) | TRPA1 | |
| SCHEMBL15075855 | 0.71 | — | — | |
| SCHEMBL9926021 | 0.71 | TRPA1 (0.58) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338314-A | [1,2]Anellated-7-phenyl-1,4-benzodiazepine and pharmaceutical compositions thereof and use for treatment of ulcers | KALI-CHEMIE PHARMA GMBH (DE) | 1982-07-06 | — | — | US | disclosed |
| EP-0004024-B1 | METHOD FOR PREPARING 3-HYDROXY-6-PHENYL-1,2,3,4-TETRAHYDRO-1,5-BENZODIAZOCINES | Kali-Chemie Pharma GmbH (DE) | 1982-02-24 | — | — | EP | disclosed |
| EP-0008045-B1 | (1,2)-ANNELLATED 7-PHENYL-1,4-BENZODIAZEPINE DERIVATIVES AND SALTS THEREOF, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Kali-Chemie Pharma GmbH (DE) | 1981-09-30 | — | — | EP | disclosed |
| US-4244869-A | HEATING AN ACYLDIAMINE IN THE PRESENCE OF PHOSPHORUS OXYCHLORIDE FOLLOWED BY REACTION WITH AN ALKALI METAL COMPOUND | KALI-CHEMIE A.G. (DE) | 1981-01-13 | — | — | US | disclosed |
| EP-0008045-A1 | (1,2)-Annellated 7-phenyl-1,4-benzodiazepine derivatives and salts thereof, processes for their preparation and medicaments containing them | Kali-Chemie Pharma GmbH (DE) | 1980-02-20 | — | — | EP | disclosed |
| EP-0004024-A2 | Method for preparing 3-hydroxy-6-phenyl-1,2,3,4-tetrahydro-1,5-benzodiazocines | Kali-Chemie Pharma GmbH (DE) | 1979-09-19 | — | — | EP | disclosed |
| US-4098786-A | ANTICONVULSANTS, SEDATIVES, MUSCLE RELAXANTS | KALI-CHEMIE AKTIENGESELLSCHAFT (DE) | 1978-07-04 | — | — | US | disclosed |
| US-4089953-A | 1,5-Benzodiazocines | DDSA PHARMACEUTICALS (EN) | 1978-05-16 | — | — | US | disclosed |
| US-4089953-A | 1,5-Benzodiazocines | DDSA PHARMACEUTICALS (EN) | 1978-05-16 | — | — | US | disclosed |