Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341302 | 0.87 | SIGMAR1 (0.46) | FUCA1ACHESIGMAR1MAPT | |
| SCHEMBL7346143 | 0.84 | SIGMAR1 (0.41) | MC4RFUCA1ACHESIGMAR1MAPT | |
| SCHEMBL7343513 | 0.80 | FUCA1 (0.49) | MC4RFUCA1ACHESIGMAR1MAPT | |
| SCHEMBL31288959 | 0.77 | MC4R (0.50) | MC4RACHESIGMAR1KMT2ALMNA | |
| SCHEMBL1088536 | 0.75 | FUCA1 (0.60) | FUCA1ACHESIGMAR1 | |
| Hydrochloric Acid SCHEMBL17375903 | 0.73 | FUCA1 (0.58) | FUCA1ACHESIGMAR1 | |
| Hydrochloric Acid SCHEMBL1816800 | 0.73 | FUCA1 (0.58) | FUCA1ACHESIGMAR1 | |
| SCHEMBL7338668 | 0.72 | BCHE (0.38) | MC4RACHEMAPTKDM4EMEN1 | |
| SCHEMBL3604123 | 0.72 | SIGMAR1 (0.65) | MC4RFUCA1ACHESIGMAR1LMNA | |
| SCHEMBL7373984 | 0.71 | MC4R (0.64) | MC4RACHESIGMAR1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4624961-A | LEARNING ENHANCEMENT | A. H. ROBINS COMPANY, INCORPORATED (US) | 1986-11-25 | — | — | US | disclosed |
| US-4358599-A | Synthesis of 4-amino-1,2-hydrocarbyl pyrazolidines via 4-nitro analogs | A. H. ROBINS COMPANY, INC. (US) | 1982-11-09 | — | — | US | disclosed |
| US-4309552-A | Synthesis of 4-nitro-1,2-hydrocarbyl pyrazolidines and process for preparation thereof | A. H. ROBINS COMPANY, INC. (US) | 1982-01-05 | — | — | US | disclosed |
| US-4207327-A | N-(4-Pyrazolidinyl)benzamides and their amino precursors | A. H. ROBINS COMPANY, INC. (US) | 1980-06-10 | — | — | US | disclosed |