Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.47 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336000 | 0.83 | F2 (0.50) | ITGA1F2MEN1KMT2A | |
| SCHEMBL7056979 | 0.81 | F2 (0.57) | TDP1ITGA1F2MEN1KMT2A | |
| SCHEMBL5866138 | 0.81 | MEN1 (0.48) | TDP1SMN1; SMN2MAOBALDH1A1ALPL | |
| SCHEMBL4622013 | 0.78 | TDP1 (0.64) | TDP1ENPP3ENPP1SMN1; SMN2MAOB | |
| SCHEMBL2238589 | 0.78 | TDP1 (0.66) | TDP1ENPP3ENPP1SMN1; SMN2MAOB | |
| SCHEMBL7336916 | 0.78 | ALDH1A1 (0.55) | TDP1ENPP3ENPP1SMN1; SMN2MAOB | |
| SCHEMBL7327550 | 0.78 | TDP1 (0.53) | TDP1ENPP3ENPP1ALDH1A1F2 | |
| SCHEMBL7334799 | 0.77 | F2 (0.55) | TDP1SMN1; SMN2MAOBALDH1A1MAPT | |
| SCHEMBL165491 | 0.75 | TDP1 (1.00) | TDP1ENPP3ENPP1SMN1; SMN2MAOB | |
| SCHEMBL9495042 | 0.75 | TDP1 (0.67) | TDP1ENPP3ENPP1SMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |