Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RRM2 | P31350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1924747 | 0.87 | MAPT (0.57) | MAPTGAAIDO1TNIKEDNRA | |
| SCHEMBL7360731 | 0.86 | MAPT (0.43) | MAPTGAAALDH1A1ARCA1 | |
| SCHEMBL2059186 | 0.85 | ABL1 (0.49) | MAPTALDH1A1 | |
| SCHEMBL27619421 | 0.83 | ABL1 (0.51) | MAPTALDH1A1 | |
| SCHEMBL8744011 | 0.83 | ABL1 (0.51) | MAPTALDH1A1 | |
| SCHEMBL27342096 | 0.83 | ABL1 (0.51) | MAPTALDH1A1 | |
| SCHEMBL222582 | 0.83 | ABL1 (0.51) | MAPTALDH1A1 | |
| SCHEMBL221358 | 0.83 | ABL1 (0.51) | MAPTALDH1A1 | |
| SCHEMBL3061946 | 0.80 | MAPT (0.48) | MAPTGAAIDO1ALDH1A1MEN1 | |
| SCHEMBL11020309 | 0.80 | MAPT (0.50) | MAPTGAAIDO1TNIKEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435503-B1 | Improvements in or relating to gylcopeptide derivatives | LILLY CO ELI (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5591714-A | TREATING VANCOMYCIN RESISTANT ENTEROCOCCUS INFECTIONS WITH GLYCOPEPTIDE ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 1997-01-07 | — | — | US | disclosed |
| EP-0435503-A1 | Improvements in or relating to gylcopeptide derivatives | ELI LILLY AND COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |