Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385681 | 0.79 | TDP1 (0.35) | TDP1 | |
| SCHEMBL10351152 | 0.78 | OPRD1 (0.42) | TDP1OPRD1MEN1KMT2A | |
| SCHEMBL16757387 | 0.77 | TDP1 (0.42) | TDP1OPRD1CYP2D6 | |
| SCHEMBL9844393 | 0.76 | OPRD1 (0.42) | TDP1OPRD1 | |
| Hydrochloric Acid SCHEMBL8693217 | 0.76 | TDP1 (0.43) | TDP1MEN1KMT2ACYP2D6 | |
| SCHEMBL16757280 | 0.76 | TDP1 (0.46) | TDP1OPRD1MEN1KMT2ACYP2D6 | |
| SCHEMBL5683230 | 0.76 | TDP1 (0.41) | TDP1OPRD1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6540416 | 0.75 | MEN1 (0.42) | TDP1MEN1KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL6540563 | 0.75 | MEN1 (0.42) | TDP1MEN1KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL6541247 | 0.75 | MEN1 (0.42) | TDP1MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4225955-A | — | — | None | — | — | JP | disclosed |
| US-5215987-A | Carbdiotonic agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| US-5215987-A | Carbdiotonic agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| JP-H04225955-A | SUBSTITUTED BENZHYDRYL 2-HYDROXYPROPYL PIPERAZINE DERIVATIVE | ORTHO PHARMACEUT CORP | 1992-08-14 | — | — | JP | disclosed |
| EP-0458459-A2 | Substituted benzhydryl 2-hydroxypropyl piperazine derivatives | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-11-27 | — | — | EP | disclosed |
| EP-0458459-A2 | Substituted benzhydryl 2-hydroxypropyl piperazine derivatives | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-11-27 | — | — | EP | disclosed |
| EP-0458459-A2 | Substituted benzhydryl 2-hydroxypropyl piperazine derivatives | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-11-27 | — | — | EP | disclosed |