Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 19/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9241574 | 1.00 | CASP1 (0.59) | CASP1 | |
| SCHEMBL9696739 | 1.00 | CASP1 (0.59) | CASP1 | |
| SCHEMBL10888856 | 0.90 | CASP1 (0.59) | CASP1 | |
| SCHEMBL10884952 | 0.90 | CASP1 (0.59) | CASP1 | |
| SCHEMBL4679345 | 0.88 | CASP1 (0.48) | CASP1 | |
| SCHEMBL4679349 | 0.88 | CASP1 (0.48) | CASP1 | |
| SCHEMBL28836378 | 0.87 | CASP1 (0.47) | CASP1 | |
| SCHEMBL28836379 | 0.87 | CASP1 (0.47) | CASP1 | |
| SCHEMBL6808276 | 0.85 | CASP1 (0.46) | CASP1 | |
| SCHEMBL12522512 | 0.85 | CASP1 (0.62) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866545-A | ANTIINFLAMMATORY AGENTS; NERVOUS SYSTEM DISORDERS; GASTROINTESTINAL DISORDERS; UROGENITAL DISORDERS | MERCK & CO., INC. (US) | 1999-02-02 | — | — | US | disclosed |
| EP-0648128-A4 | DNA ENCODING PRECURSOR INTERLEUKIN 1-g(b) CONVERTING ENZYME. | MERCK & CO INC (US) | 1995-07-26 | — | — | EP | disclosed |
| EP-0648128-A1 | DNA ENCODING PRECURSOR INTERLEUKIN 1$g(b) CONVERTING ENZYME | MERCK & CO. INC. (US) | 1995-04-19 | — | — | EP | disclosed |
| WO-1995005192-A1 | SUBSTITUTED KETONE DERIVATIVES AS INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | MERCK & CO., INC. (US) | 1995-02-23 | — | — | WO | disclosed |
| WO-1994000154-A1 | DNA ENCODING PRECURSOR INTERLEUKIN 1β CONVERTING ENZYME | MERCK & CO., INC. (US) | 1994-01-06 | — | — | WO | disclosed |
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |
| US-4540579-A | 2-[(R) Amino acid alkyl]penems | SCHERING CORPORATION (US) | 1985-09-10 | — | — | US | disclosed |