Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | POLA1 | P09884 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337368 | 1.00 | NOTUM (0.48) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL7344895 | 1.00 | NOTUM (0.48) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL8742962 | 0.86 | NOTUM (0.45) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL8742991 | 0.86 | NOTUM (0.45) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL8742995 | 0.86 | NOTUM (0.45) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL7343593 | 0.82 | NOTUM (0.50) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL7343587 | 0.82 | NOTUM (0.50) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL3820385 | 0.81 | HSD17B10 (0.48) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL7336655 | 0.80 | NOTUM (0.48) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL7338202 | 0.80 | NOTUM (0.48) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699680-B1 | Oxazoloquinolinone derivatives, their preparation and their use in therapy | SANOFI SYNTHELABO (FR) | 2000-03-08 | — | — | EP | disclosed |
| US-5641785-A | ANTIDEPRESSANTS, NERVOUS SYSTEM DISORDERS | SYNTHELABO (FR) | 1997-06-24 | — | — | US | disclosed |
| EP-0699680-A1 | Oxazoloquinolinone derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1996-03-06 | — | — | EP | disclosed |