Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8742995 | 1.00 | NOTUM (0.45) | NOTUMKDM4ENPSR1MTNR1AHSD17B10 | |
| SCHEMBL8742962 | 1.00 | NOTUM (0.45) | NOTUMKDM4ENPSR1MTNR1AHSD17B10 | |
| SCHEMBL7337368 | 0.86 | NOTUM (0.48) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL7337365 | 0.86 | NOTUM (0.48) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL7344895 | 0.86 | NOTUM (0.48) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL8742789 | 0.83 | MTNR1A (0.48) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL7305955 | 0.83 | MTNR1A (0.48) | NOTUMMTNR1AHSD17B10ALDH1A1LMNA | |
| SCHEMBL8742926 | 0.82 | MTNR1A (0.47) | NOTUMKDM4ENPSR1MTNR1AHSD17B10 | |
| SCHEMBL8742853 | 0.82 | MTNR1A (0.47) | NOTUMKDM4ENPSR1MTNR1AHSD17B10 | |
| SCHEMBL7316234 | 0.82 | MTNR1A (0.47) | NOTUMKDM4ENPSR1MTNR1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641785-A | ANTIDEPRESSANTS, NERVOUS SYSTEM DISORDERS | SYNTHELABO (FR) | 1997-06-24 | — | — | US | disclosed |