Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CPA3 | P15088 | 3/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 4/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337786 | 0.88 | GAA (0.39) | CYP1A2GFERKMT2ACTSSL3MBTL1 | |
| SCHEMBL9437595 | 0.83 | KMT2A (0.37) | CYP1A2CPA3FOLH1GFERKMT2A | |
| SCHEMBL9437590 | 0.83 | KMT2A (0.37) | CYP1A2CPA3FOLH1GFERKMT2A | |
| SCHEMBL9437599 | 0.83 | CTSS (0.36) | CYP1A2CPA3FOLH1GFERKMT2A | |
| SCHEMBL9437665 | 0.83 | F2 (0.42) | CTSS | |
| SCHEMBL9437544 | 0.82 | ALOX5AP (0.35) | GFERKMT2ACTSSL3MBTL1PKM | |
| SCHEMBL9437581 | 0.81 | CTSS (0.35) | GFERKMT2ACTSSL3MBTL1PKM | |
| SCHEMBL9437633 | 0.81 | CTSS (0.37) | GFERKMT2ACTSSL3MBTL1PKM | |
| SCHEMBL7334299 | 0.80 | MME (0.47) | — | |
| SCHEMBL7333389 | 0.79 | CYP1A2 (0.54) | CYP1A2CPA3FOLH1KMT2ACPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456185-B1 | Renin inhibitors | ABBOTT LAB (US) | 1995-05-31 | — | — | EP | disclosed |
| US-5332742-A | Ocular hypotensive | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |
| US-5310740-A | Congestive heart failure, hypotensive agents, antiglaucoma agents; side effect reduction | ABBOTT LABORATORIES (US) | 1994-05-10 | — | — | US | disclosed |
| US-5284849-A | Treating hypertension and congestive heart failure | ABBOTT LABORATORIES (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0456185-A2 | Renin inhibitors | ABBOTT LABORATORIES (US) | 1991-11-13 | — | — | EP | disclosed |