Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.38 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334894 | 0.92 | ITGB3 (0.69) | ITGB3ITGA2BALOX15KMT2AALDH1A1 | |
| SCHEMBL7341525 | 0.88 | ITGB3 (0.49) | ITGB3ITGA2BALOX15KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7345194 | 0.87 | ITGB3 (0.62) | ITGB3ITGA2BALOX15KMT2AALDH1A1 | |
| SCHEMBL7310389 | 0.83 | ITGB3 (0.52) | ITGB3ITGA2BALOX15KMT2AALDH1A1 | |
| SCHEMBL7337962 | 0.83 | ITGB3 (0.68) | ITGB3ITGA2BALOX15KMT2AALDH1A1 | |
| SCHEMBL7335544 | 0.81 | ITGB3 (0.66) | ITGB3ITGA2BALOX15KMT2AALDH1A1 | |
| SCHEMBL8043652 | 0.81 | ITGB3 (0.41) | ITGB3ITGA2BALOX15KMT2AALDH1A1 | |
| SCHEMBL7342517 | 0.80 | ITGB3 (0.53) | ITGB3ITGA2BALOX15KMT2AALDH1A1 | |
| SCHEMBL7313512 | 0.79 | ITGB3 (0.48) | ITGB3ITGA2BALOX15KMT2AALDH1A1 | |
| SCHEMBL7337509 | 0.79 | ITGB3 (0.52) | ITGB3ITGA2BALOX15KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090273-A | Acetogenin | GLAXO GROUP LTD (GB) | 1994-08-03 | — | — | CN | claimed |
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | claimed |
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |