Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.61 |
| ▸ | MYC | P01106 | 4/20 | 0.57 |
| ▸ | MAX | P61244 | 3/20 | 0.57 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342694 | 0.91 | MYC (0.68) | ARPELP1MYCMAXEP300 | |
| SCHEMBL7372078 | 0.85 | AR (0.58) | ARPELP1MYCMAXMAPT | |
| SCHEMBL16392518 | 0.82 | AR (0.71) | ARPELP1MYCMAXMAPT | |
| SCHEMBL7338638 | 0.81 | MAPT (0.46) | ARPELP1MAPTALDH1A1KMT2A | |
| SCHEMBL7376464 | 0.78 | MYC (0.52) | ARPELP1MYCMAXEP300 | |
| SCHEMBL12068720 | 0.77 | MYC (0.85) | ARPELP1MYCMAXEP300 | |
| SCHEMBL7343440 | 0.77 | MAPT (0.49) | ARPELP1MYCMAXEP300 | |
| SCHEMBL12068709 | 0.76 | AR (1.00) | ARPELP1MYCMAXEP300 | |
| SCHEMBL7370166 | 0.76 | CYP19A1 (0.66) | MYCMAXMAPTALDH1A1KMT2A | |
| SCHEMBL7336946 | 0.76 | MAPT (0.55) | MAPTKMT2ALMNAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |