Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14220798 | 0.84 | MAPT (0.72) | MAPTRAB9ALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL7345433 | 0.83 | MAPT (0.56) | MAPTRAB9ALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL15871980 | 0.79 | APP (0.53) | MAPTLMNAL3MBTL1SMN1; SMN2CYP1A2 | |
| SCHEMBL23434862 | 0.78 | MAPT (0.54) | MAPTRAB9ALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL13413481 | 0.76 | MAPT (0.58) | MAPTRAB9ALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL13413479 | 0.76 | MAPT (0.58) | MAPTRAB9ALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL15703639 | 0.76 | MAPT (0.62) | MAPTRAB9ALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL23434965 | 0.76 | MAPT (0.52) | MAPTRAB9ALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6864193 | 0.76 | LMNA (0.49) | MAPTRAB9ALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL7337537 | 0.76 | AR (0.61) | MAPTRAB9ALMNAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |