Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 5/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337579 | 0.92 | AVPR2 (0.34) | AVPR2AVPR1AAVPR1BTDP1MAP3K7 | |
| SCHEMBL7336265 | 0.91 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BL3MBTL1MAP3K7 | |
| SCHEMBL7336166 | 0.91 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BL3MBTL1MAP3K7 | |
| Hydrochloric Acid SCHEMBL7773784 | 0.91 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BL3MBTL1MAP3K7 | |
| Hydrochloric Acid SCHEMBL7335182 | 0.91 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BL3MBTL1MAP3K7 | |
| Hydrochloric Acid SCHEMBL7345642 | 0.91 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BL3MBTL1MAP3K7 | |
| SCHEMBL7338927 | 0.89 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BMAP3K7ALDH1A1 | |
| Sulfuric Acid SCHEMBL7344173 | 0.89 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1BMAP3K7CCR8 | |
| SCHEMBL7340231 | 0.89 | AVPR2 (0.45) | AVPR2AVPR1AAVPR1BMAP3K7 | |
| SCHEMBL7346393 | 0.88 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BMAP3K7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |