SCHEMBL7337602

SCHEMBL7337602

COc1cc(N)c(Cl)cc1C(=O)NC1CN(C)N(C)C1

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 6/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7337280 0.90 HTR4 (0.66) HTR4
Hydrochloric Acid SCHEMBL7340606 0.89 HTR4 (0.64) HTR4
SCHEMBL7339591 0.87 HTR4 (0.65) HTR4
SCHEMBL15650737 0.87 HTR4 (0.83) HTR4
Dazopride SCHEMBL184075 0.87 HTR4 (0.72) HTR4
SCHEMBL10827995 0.87 HTR4 (0.67) HTR4
SCHEMBL7345151 0.86 DRD4 (0.72) HTR4
Dazopride SCHEMBL7339808 0.86 HTR4 (0.71) HTR4
SCHEMBL11557104 0.86 HTR4 (0.72) HTR4
SCHEMBL15651948 0.85 HTR4 (0.78) HTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4624961-A LEARNING ENHANCEMENT A. H. ROBINS COMPANY, INCORPORATED (US) 1986-11-25 US claimed
US-4207327-A N-(4-Pyrazolidinyl)benzamides and their amino precursors A. H. ROBINS COMPANY, INC. (US) 1980-06-10 US claimed
US-4624961-A LEARNING ENHANCEMENT A. H. ROBINS COMPANY, INCORPORATED (US) 1986-11-25 US disclosed
US-4547518-A Antiemetic N-(1-substituted-4,5-dihydro-1H-pyrazol-4-yl)benzamides A. H. ROBINS COMPANY, INCORPORATED (US) 1985-10-15 US disclosed
US-4207327-A N-(4-Pyrazolidinyl)benzamides and their amino precursors A. H. ROBINS COMPANY, INC. (US) 1980-06-10 US disclosed