Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348272 | 0.97 | HDAC3 (0.35) | ALDH1A1KDM4EHDAC3HDAC1MAPT | |
| SCHEMBL7344082 | 0.92 | HDAC3 (0.35) | ALDH1A1HDAC3HDAC1MAPTHTT | |
| SCHEMBL7338581 | 0.92 | HDAC3 (0.36) | ALDH1A1HDAC3HDAC1MAPTHTT | |
| SCHEMBL7347827 | 0.92 | MAPT (0.36) | ALDH1A1HDAC3HDAC1MAPTHTT | |
| SCHEMBL7339526 | 0.89 | HDAC3 (0.34) | ALDH1A1HDAC3HDAC1MAPTHTT | |
| SCHEMBL7336405 | 0.89 | MAPT (0.37) | ALDH1A1HDAC3HDAC1MAPTHTT | |
| SCHEMBL7346426 | 0.89 | MAPT (0.41) | ALDH1A1MAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL7337072 | 0.89 | ALDH1A1 (0.34) | ALDH1A1HDAC3HDAC1MAPTHTT | |
| SCHEMBL7346836 | 0.89 | HDAC3 (0.36) | ALDH1A1HDAC3HDAC1CYP3A4KMT2A | |
| SCHEMBL7348293 | 0.89 | MAPT (0.37) | ALDH1A1MAPTHTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |