⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046930 | 1.00 | — | — | |
| SCHEMBL7814020 | 0.78 | — | — | |
| SCHEMBL1059084 | 0.78 | — | — | |
| SCHEMBL1059082 | 0.78 | — | — | |
| SCHEMBL1247337 | 0.72 | — | — | |
| SCHEMBL19418916 | 0.72 | AKT1 (0.33) | — | |
| SCHEMBL12817553 | 0.71 | — | — | |
| SCHEMBL7362820 | 0.71 | — | — | |
| SCHEMBL7362823 | 0.71 | — | — | |
| SCHEMBL7728055 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594835-A4 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS INC (US) | 2007-05-02 | — | — | EP | claimed |
| US-20060173199-A1 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses | HONG BORCHERNG | 2006-08-03 | — | — | US | claimed |
| EP-1594835-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | Auspex Pharmaceuticals, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| WO-2004064745-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS, INC. (US) | 2004-08-05 | — | — | WO | claimed |
| US-5837873-A | PROTECTED OXYDIAMINES | ABBOTT LABORATORIES (US) | 1998-11-17 | — | — | US | claimed |
| CN-117024469-A | Macrocyclization reactions useful for the synthesis of halichondrin macrolides, intermediates and other fragments | 卫材R&D管理有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-112250692-B | Macrocyclization reactions useful for the synthesis of halichondrin macrolides, intermediates and other fragments | 卫材R&D管理有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116615411-A | Process for producing peptide compound containing N-substituted amino acid residue | 中外制药株式会社 | 2023-08-18 | — | — | CN | disclosed |
| CN-116547295-A | Method for supporting amino acid on resin for solid phase synthesis | 中外制药株式会社 | 2023-08-04 | — | — | CN | disclosed |
| CN-114805322-A | Prins reactions and intermediates useful for the synthesis of halichondrin macrolides and analogs thereof | 卫材R&D管理有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114716453-A | Macrocyclization reactions and intermediates useful in the synthesis of analogs of halichondrin B | 卫材R&D管理有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-109942560-B | Macrocyclization reactions and intermediates useful in the synthesis of analogs of halichondrin B | 卫材R&D管理有限公司 | 2022-06-17 | — | — | CN | disclosed |
| EP-0318860-B1 | SUBSTITUTED ALKYLAMINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-5211739-A | Herbicidal-1-(disubstituted carbamoyl or thiocarbamoyl)-1,2,4-triazol-3-yl sulfonates and thisulfonates | ROHM AND HAAS COMPANY (US) | 1993-05-18 | — | — | US | disclosed |
| EP-0524401-A1 | Thiazolazo dyestuffs with a coupling component of the diphenylamine series | BASF Aktiengesellschaft (DE) | 1993-01-27 | — | — | EP | disclosed |
| EP-0318860-A2 | Substituted alkylamine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |
| EP-0216299-A1 | Quinoxaline derivatives, method for their preparartion and their use to protect cultivated plants against phytotoxical reaction of herbicides | BASF Aktiengesellschaft (DE) | 1987-04-01 | — | — | EP | disclosed |
| US-4470421-A | SMOKING COMPOSITIONS CONTAINING A POLYMERIZABLE OR POLYMERIZED MALONATE FLAVOR ADDITIVE | PHILIP MORRIS, INCORPORATED (US) | 1984-09-11 | — | — | US | disclosed |
| US-4140514-A | HERBICIDES | CHEVRON RESEARCH COMPANY (US) | 1979-02-20 | — | — | US | disclosed |
| US-3957928-A | S-AMMONIUM-O-HYDROCARBYL-N-ACYL PHOSPHORAMIDOTHIOATE SALT PRODUCTION AND REACTION WITH ALKYLATING AGENT | CHEVRON RESEARCH COMPANY (US) | 1976-05-18 | — | — | US | disclosed |