Phosphoric Acid

Phosphoric Acid

SCHEMBL733844

O.O=P([O-])([O-])O.O=P([O-])([O-])O.[Ca+2].[Ca+2]

nearest known ligand 0.58

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 1/20 0.58
LMNA P02545 2/20 0.40
KDM4E B2RXH2 2/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
CA2 P00918 1/20 0.39
MMP2 P08253 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
FDPS P14324 1/20 0.33
BLM P54132 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA1 P00915 2/20 0.30
CA4 P22748 2/20 0.30
CA5A P35218 2/20 0.30
CA5B Q9Y2D0 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL3306696 1.00 SLC34A1 (0.58) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL1742995 1.00 SLC34A1 (0.58) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL4611532 1.00
Phosphoric Acid SCHEMBL733843 1.00
Phosphoric Acid SCHEMBL166796 1.00
Phosphoric Acid SCHEMBL7871826 0.95
Phosphoric Acid SCHEMBL7871824 0.95 SLC34A1 (0.54) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL21612686 0.95 SLC34A1 (0.54) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL22116976 0.95 SLC34A1 (0.54) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL5330837 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120070585-A1 MANGANESE BASED COATING FOR WEAR AND CORROSION RESISTANCE CATERPILLAR INC. 2012-03-22 US disclosed
US-8137761-B2 Method of coating and induction heating a component CATERPILLAR INC. (US) 2012-03-20 US disclosed
US-8137805-B2 Manganese based coating for wear and corrosion resistance CATERPILLAR INC. (US) 2012-03-20 US disclosed
US-20090311545-A1 Method of coating and induction heating a component CATERPILLAR INC. 2009-12-17 US disclosed
US-20080318035-A1 Manganese based coating for wear and corrosion resistance CATERPILLAR INC. 2008-12-25 US disclosed
EP-1714664-A2 Superabsorbent polymer containing triclosan as odor-controlling compound BASF AKTIENGESELLSCHAFT (DE) 2006-10-25 EP disclosed
EP-1173234-B1 SUPERABSORBENT POLYMER CONTAINING ODOR CONTROLLING COMPOUNDS BASF AG (DE) 2006-04-26 EP disclosed
US-6444134-B1 SOLVENT, ETCHING, RINSING, FINISHING THE FLECTO COMPANY, INC. 2002-09-03 US disclosed
CN-1349420-A Superabsorbent polymer containing odor controlling compounds BASF CORP (DE) 2002-05-15 CN disclosed
EP-1173234-A1 SUPERABSORBENT POLYMER CONTAINING ODOR CONTROLLING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2002-01-23 EP disclosed
US-6229062-B1 WITH CYCLODEXTRAN, TRICLOSAN, AMPHOTERIC SURFACTANT, OR WATER INSOLUBLE PHOSPHATE AS ODOR CONTROLLER HOMOGENOUSLY DISTRIBUTED IN POLYMER; USED IN BANDAGES, DIAPERS, SANITARY NAPKINS, AND OTHER DIPOSABLE PAPER PRODUCTS BASF AKTIENGESELLSCHAFT CORPORATION (DE) 2001-05-08 US disclosed
WO-2000066187-A1 SUPERABSORBENT POLYMER CONTAINING ODOR CONTROLLING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2000-11-09 WO disclosed
US-5489420-A SELECTIVE NONCATALYTIC REDUCTION IN GAS PHASE AT HIGH TEMPERATURES BY USING AN NH-CONTAINING REDUCING AGENT SUCH AS UREA NALCO FUEL TECH (US) 1996-02-06 US disclosed
WO-1995024357-A1 PROCESS AND COMPOSITION FOR POLLUTION CONTROL NALCO FUEL TECH (US) 1995-09-14 WO disclosed