Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 1/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.56 |
| ▸ | REN | P00797 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | CPA1 | P15085 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | YAP1 | P46937 | 3/20 | 0.51 |
| ▸ | BCL2 | P10415 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338616 | 1.00 | IL1RN (0.56) | IL1RNERAP2ERAP1RENLTA4H | |
| Hydrochloric Acid SCHEMBL8414461 | 0.89 | ERAP2 (0.66) | IL1RNERAP2ERAP1LTA4HMME | |
| SCHEMBL7346373 | 0.88 | IL1RN (0.59) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7346379 | 0.88 | IL1RN (0.59) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7348670 | 0.87 | IL1RN (0.58) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7348677 | 0.87 | IL1RN (0.58) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7366803 | 0.87 | IL1RN (0.56) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7373579 | 0.87 | IL1RN (0.56) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7338162 | 0.87 | MME (0.56) | IL1RNERAP2ERAP1RENLTA4H | |
| SCHEMBL7344077 | 0.87 | PPARG (0.60) | IL1RNERAP2ERAP1LTA4HMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |