Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.56 |
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | CPA1 | P15085 | 3/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.56 |
| ▸ | IL1RN | P18510 | 1/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.55 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.55 |
| ▸ | REN | P00797 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | LAP3 | P28838 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346037 | 0.91 | IL1RN (0.53) | MMEACECPA1ACE2IL1RN | |
| SCHEMBL7339698 | 0.91 | IL1RN (0.53) | MMEACECPA1ACE2IL1RN | |
| SCHEMBL7339406 | 0.89 | LNPEP (0.55) | MMEACECPA1ACE2IL1RN | |
| SCHEMBL7364989 | 0.88 | MME (0.56) | MMEACECPA1ACE2IL1RN | |
| SCHEMBL7341980 | 0.88 | MME (0.52) | MMEACECPA1ACE2IL1RN | |
| SCHEMBL7344077 | 0.88 | PPARG (0.60) | MMEACECPA1ACE2IL1RN | |
| SCHEMBL7343134 | 0.87 | MMP1 (0.52) | MMP9MMP8CACNA1BLTA4H | |
| SCHEMBL7348068 | 0.87 | PSMB5 (0.51) | MMEACECPA1ACE2ERAP2 | |
| SCHEMBL7421818 | 0.87 | LTA4H (0.50) | MMEACECPA1ACE2IL1RN | |
| SCHEMBL7338616 | 0.87 | IL1RN (0.56) | MMEACECPA1ACE2IL1RN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |