SCHEMBL7339018

SCHEMBL7339018

CN1CC(Nc2ccccc2)CN1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.49
PRMT6 Q96LA8 1/20 0.49
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
PKM P14618 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
RAD52 P43351 1/20 0.43
GFER P55789 1/20 0.43
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
POLB P06746 1/20 0.39
CCR6 P51684 1/20 0.38
TSHR P16473 1/20 0.37
ADORA3 P0DMS8 2/20 0.37
ADORA2A P29274 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12049585 0.87 CARM1 (0.49) CARM1PRMT6ALDH1A1MEN1LMNA
SCHEMBL11253819 0.82 ALDH1A1 (0.45) CARM1PRMT6ALDH1A1MEN1LMNA
SCHEMBL12026516 0.79 CARM1 (0.42) CARM1PRMT6ALDH1A1MEN1LMNA
Hydrochloric Acid SCHEMBL11241402 0.79 ALDH1A1 (0.43) CARM1PRMT6ALDH1A1MEN1LMNA
Hydrochloric Acid SCHEMBL11241377 0.79 ALDH1A1 (0.43) CARM1PRMT6ALDH1A1MEN1LMNA
SCHEMBL7346711 0.78 CARM1 (0.45) CARM1PRMT6ALDH1A1MEN1LMNA
SCHEMBL11236449 0.76 CARM1 (0.55) CARM1PRMT6POLBCCR6CA12
SCHEMBL2912672 0.76 KMT2A (0.43) ALDH1A1MEN1LMNAMAPTKMT2A
SCHEMBL2674960 0.75 POLB (0.68) CARM1PRMT6POLBCCR6CA12
SCHEMBL28613745 0.75 ALDH1A1 (0.40) CARM1PRMT6ALDH1A1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4207327-A N-(4-Pyrazolidinyl)benzamides and their amino precursors A. H. ROBINS COMPANY, INC. (US) 1980-06-10 US disclosed