Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.65 |
| ▸ | LAP3 | P28838 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338844 | 1.00 | LTA4H (0.65) | LTA4HLAP3MAOBPPARGPPARA | |
| SCHEMBL7338836 | 1.00 | LTA4H (0.65) | LTA4HLAP3MAOBPPARGPPARA | |
| SCHEMBL7991533 | 0.90 | LTA4H (0.55) | LTA4HLAP3MAOBPPARGPPARA | |
| SCHEMBL7341088 | 0.90 | MAOB (0.55) | LTA4HLAP3MAOBPPARAFFAR1 | |
| SCHEMBL7341100 | 0.90 | MAOB (0.55) | LTA4HLAP3MAOBPPARAFFAR1 | |
| SCHEMBL12656179 | 0.89 | LTA4H (0.60) | LTA4HLAP3MAOBPPARGPPARA | |
| SCHEMBL7806363 | 0.88 | LTA4H (0.56) | LTA4HLAP3MAOBPPARGPPARA | |
| SCHEMBL594132 | 0.88 | SLC7A5 (0.58) | LTA4HPTGS1 | |
| SCHEMBL314142 | 0.88 | SLC7A5 (0.58) | LTA4HPTGS1 | |
| SCHEMBL1221379 | 0.88 | SLC7A5 (0.58) | LTA4HPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |