Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312875 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BCA1CA2ZDHHC7 | |
| Hydrochloric Acid SCHEMBL7312863 | 0.98 | ITGB3 (0.44) | ITGB3ITGA2BCA1CA2ZDHHC7 | |
| Hydrochloric Acid SCHEMBL7312868 | 0.98 | ITGB3 (0.44) | ITGB3ITGA2BCA1CA2ZDHHC7 | |
| SCHEMBL7417484 | 0.89 | ITGB3 (0.44) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL6935765 | 0.89 | ITGB3 (0.44) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8741792 | 0.88 | ITGB3 (0.46) | ITGB3ITGA2BCA1CA2ZDHHC7 | |
| SCHEMBL8741789 | 0.88 | ITGB3 (0.46) | ITGB3ITGA2BCA1CA2ZDHHC7 | |
| Hydrochloric Acid SCHEMBL7436626 | 0.86 | ITGB3 (0.45) | ITGB3ITGA2BCA1CA2ZDHHC7 | |
| Hydrochloric Acid SCHEMBL7436619 | 0.86 | ITGB3 (0.45) | ITGB3ITGA2BCA1CA2ZDHHC7 | |
| SCHEMBL7262649 | 0.83 | ITGB3 (0.52) | ITGB3ITGA2BITGAVCHRM2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714295-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2000-12-20 | — | — | EP | disclosed |
| EP-0863893-A1 | FIBRINOGEN RECEPTOR ANTAGONIST | Merck & Co., Inc. (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5786373-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-07-28 | — | — | US | disclosed |
| EP-0781133-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1997-12-10 | — | — | EP | disclosed |
| US-5648368-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0698023-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1997-07-02 | — | — | EP | disclosed |
| EP-0781133-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1997-07-02 | — | — | EP | disclosed |
| WO-1997015568-A1 | FIBRINOGEN RECEPTOR ANTAGONIST | MERCK & CO., INC. (US) | 1997-05-01 | — | — | WO | disclosed |
| EP-0667773-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0714295-A4 | — | — | 1996-07-10 | — | — | EP | disclosed |
| EP-0673247-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0698023-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| US-5494921-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1996-02-27 | — | — | US | disclosed |
| EP-0673247-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-09-27 | — | — | EP | disclosed |
| EP-0667773-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-08-23 | — | — | EP | disclosed |
| US-5397791-A | Anticoagulants | MERCK & CO., INC. (US) | 1995-03-14 | — | — | US | disclosed |
| WO-1995004531-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1995-02-16 | — | — | WO | disclosed |
| WO-1994026745-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-11-24 | — | — | WO | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |
| WO-1994008577-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |