Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 8/20 | 0.73 |
| ▸ | F2 | P00734 | 6/20 | 0.73 |
| ▸ | PLG | P00747 | 6/20 | 0.73 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.73 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.73 |
| ▸ | PLAT | P00750 | 6/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7336839 | 0.94 | PLAU (0.65) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL7344225 | 0.88 | PLAU (0.55) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL4309463 | 0.84 | PLAU (1.00) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL30583187 | 0.84 | PLAU (1.00) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL7337131 | 0.80 | PLAU (0.50) | PLAUF2PLGKLKB1PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7336833 | 0.79 | PLAU (0.88) | PLAUF2PLGKLKB1PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7338215 | 0.76 | PLAU (0.46) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL7344380 | 0.74 | PLAU (0.66) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL7345579 | 0.74 | PLAU (0.65) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL7335937 | 0.73 | DEGS1 (0.57) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |