Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | GRN | P28799 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6618585 | 1.00 | GAA (0.64) | GAAALDH1A1POLBCTSSMEN1 | |
| SCHEMBL6661676 | 0.87 | GAA (0.50) | GAAALDH1A1POLBCTSSCAPN1 | |
| SCHEMBL7341199 | 0.85 | GAA (0.62) | GAAALDH1A1POLBCTSSMEN1 | |
| SCHEMBL3966807 | 0.85 | GAA (0.62) | GAAALDH1A1POLBCTSSMEN1 | |
| SCHEMBL7040252 | 0.85 | GAA (0.62) | GAAALDH1A1POLBCTSSMEN1 | |
| SCHEMBL6712836 | 0.84 | GAA (0.58) | GAAALDH1A1POLBCTSSMEN1 | |
| SCHEMBL6447450 | 0.83 | GAA (0.59) | GAAALDH1A1POLBCTSSMEN1 | |
| SCHEMBL7027854 | 0.83 | CTSS (0.69) | GAAALDH1A1CTSSCAPN1 | |
| SCHEMBL6801263 | 0.83 | CTSS (0.69) | GAAALDH1A1CTSSCAPN1 | |
| SCHEMBL6447455 | 0.83 | GAA (0.59) | GAAALDH1A1POLBCTSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |