Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 6/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | OGG1 | O15527 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.45 |
| ▸ | BCL2 | P10415 | 3/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | BAD | Q92934 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534409 | 0.89 | KDM4E (0.57) | KDM4EALDH1A1HPGDKCNA3TDP1 | |
| SCHEMBL10537972 | 0.86 | KDM4E (0.59) | KDM4EALDH1A1HPGDKCNA3TDP1 | |
| SCHEMBL7339349 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1HPGDKCNA3TDP1 | |
| SCHEMBL7355381 | 0.81 | HTR1B (0.61) | KDM4EALDH1A1HPGDKCNA3TDP1 | |
| SCHEMBL5144042 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1HPGDKCNA3TDP1 | |
| SCHEMBL28354466 | 0.80 | KDM4E (0.57) | KDM4EALDH1A1HPGDKCNA3TDP1 | |
| SCHEMBL7162394 | 0.79 | HTR1B (0.62) | KDM4EALDH1A1HPGDKCNA3TDP1 | |
| SCHEMBL10597687 | 0.79 | KDM4E (0.63) | KDM4EALDH1A1HPGDKCNA3TDP1 | |
| SCHEMBL7347362 | 0.78 | KCNA3 (0.63) | KDM4EALDH1A1HPGDKCNA3TDP1 | |
| SCHEMBL6445049 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1HPGDKCNA3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008228-A | COMPRISING A MIXTURE OF CARRIER MONOGLYCERIDES OF MEDIUM CHAIN-FATTY ACIDS | HOFFMAN-LA ROCHE INC. (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0831826-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PROTEINASE INHIBITOR AND A MONOGLYCERIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996039142-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PROTEINASE INHIBITOR AND A MONOGLYCERIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1996-12-12 | — | — | WO | disclosed |