Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 12/20 | 0.61 |
| ▸ | HTR1D | P28221 | 3/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162394 | 0.91 | HTR1B (0.62) | HTR1BHTR1DSLC6A4HRH1KCNA3 | |
| SCHEMBL7347362 | 0.90 | KCNA3 (0.63) | HTR1BHTR1DSLC6A4HRH1KCNA3 | |
| SCHEMBL7347278 | 0.88 | KCNA3 (0.61) | HTR1BHTR1DSLC6A4HRH1KCNA3 | |
| SCHEMBL10767637 | 0.88 | KCNA3 (0.61) | HTR1BHTR1DSLC6A4HRH1KCNA3 | |
| SCHEMBL5289923 | 0.82 | HTR1B (0.77) | HTR1BHTR1DSLC6A4HRH1KCNA3 | |
| SCHEMBL14626804 | 0.82 | KCNA3 (0.46) | HTR1BHTR1DSLC6A4HRH1KCNA3 | |
| SCHEMBL30800894 | 0.82 | HTR1B (0.61) | HTR1BHTR1DSLC6A4HRH1KCNA3 | |
| SCHEMBL9064532 | 0.82 | HTR1B (0.61) | HTR1BHTR1DSLC6A4HRH1KCNA3 | |
| SCHEMBL6604458 | 0.81 | KDM4E (0.56) | HTR1BHTR1DSLC6A4HRH1KCNA3 | |
| SCHEMBL7339352 | 0.81 | KDM4E (0.49) | HTR1BHTR1DKCNA3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1107146-A | A process for preparing a composition containing benzoheterocycles | OTSUKA PHARMA CO LTD (JP) | 1995-08-23 | — | — | CN | disclosed |
| CN-1027505-C | Process for preparing benzoheterocyclic compounds | OTSUKA PHARMA CO LTD (JP) | 1995-01-25 | — | — | CN | disclosed |
| EP-0450097-A1 | BENZOHETEROCYCLIC COMPOUNDS. | OTSUKA PHARMA CO LTD (JP) | 1991-10-09 | — | — | EP | disclosed |
| WO-1991005549-A1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | WO | disclosed |
| CN-1051038-A | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1991-05-01 | — | — | CN | disclosed |