Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332683 | 0.96 | NPC1 (0.51) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL7333061 | 0.91 | KMT2A (0.48) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL7333819 | 0.88 | RAB9A (0.67) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL7331651 | 0.85 | SMN1; SMN2 (0.58) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL7336708 | 0.83 | KMT2A (0.52) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL7330954 | 0.79 | KMT2A (0.57) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7332608 | 0.79 | MAPT (0.54) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL7339085 | 0.77 | KMT2A (0.51) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL7332975 | 0.76 | KMT2A (0.44) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL7338994 | 0.76 | KMT2A (0.57) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475531-B1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | ASAHI CHEMICAL IND (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0475531-A1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-03-18 | — | — | EP | disclosed |