Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339114 | 0.91 | AVPR2 (0.42) | ALDH1A1HPGDAVPR2AVPR1AAVPR1B | |
| SCHEMBL7345034 | 0.91 | AVPR2 (0.40) | ALDH1A1HPGDMEN1KMT2AAVPR2 | |
| Hydrochloric Acid SCHEMBL7344511 | 0.91 | AVPR2 (0.40) | ALDH1A1HPGDMEN1KMT2AAVPR2 | |
| SCHEMBL7370102 | 0.90 | MEN1 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2ADRA1D | |
| SCHEMBL7336282 | 0.90 | AVPR2 (0.39) | ALDH1A1HPGDMEN1KMT2AAVPR2 | |
| SCHEMBL7339127 | 0.90 | AVPR2 (0.44) | ALDH1A1HPGDMEN1KMT2AAVPR2 | |
| Hydrochloric Acid SCHEMBL7345288 | 0.90 | AVPR2 (0.38) | ALDH1A1HPGDMEN1KMT2AAVPR2 | |
| SCHEMBL7338979 | 0.89 | AVPR2 (0.42) | ALDH1A1HPGDMEN1KMT2AAVPR2 | |
| Hydrochloric Acid SCHEMBL7342655 | 0.89 | AVPR2 (0.43) | ALDH1A1HPGDMEN1KMT2AAVPR2 | |
| SCHEMBL7966249 | 0.89 | MAPK11 (0.38) | ALDH1A1HPGDMEN1KMT2AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |