Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 5/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935246 | 0.84 | PTGER4 (0.47) | MAPK1NPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL13438926 | 0.84 | PTGER4 (0.47) | MAPK1NPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL8885032 | 0.81 | PTGER4 (0.43) | CNR2EPHX1EPHX2SMN1; SMN2KDM4E | |
| SCHEMBL10886234 | 0.79 | EBP (0.50) | NPC1MEN1KMT2ACYP2C19RAB9A | |
| SCHEMBL11168379 | 0.79 | KDM4E (0.59) | CNR2EPHX1EPHX2KDM4ECNR1 | |
| SCHEMBL6819449 | 0.78 | POLB (0.49) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL6814431 | 0.76 | PTGER4 (0.50) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL6956071 | 0.76 | FDFT1 (0.52) | NPC1RAB9ACNR2EPHX1EPHX2 | |
| SCHEMBL27270334 | 0.76 | PTGER4 (0.55) | MEN1KMT2AMAPTCYP2C19NPSR1 | |
| SCHEMBL17051427 | 0.76 | PTGER4 (0.47) | MEN1KMT2ACYP2C19CNR2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598962-A1 | Imidazole derivatives as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-06-01 | — | — | EP | disclosed |
| US-5296493-A | Analgesics or antiischemics | NEUROSEARCH A/S (DK) | 1994-03-22 | — | — | US | disclosed |