Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 4/20 | 0.63 |
| ▸ | PLG | P00747 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846081 | 0.99 | PLA2G4A (0.61) | PLA2G4APLGPLAUHCAR3NR1H2 | |
| SCHEMBL1749895 | 0.94 | PLA2G4A (0.59) | PLA2G4APLGPLAUHCAR3NR1H2 | |
| SCHEMBL29012864 | 0.89 | MCL1 (0.59) | PLA2G4AHCAR3MCL1BCL2TP53 | |
| SCHEMBL4934703 | 0.88 | PLA2G4A (0.55) | PLA2G4APLGPLAUHCAR3NR1H2 | |
| SCHEMBL9035319 | 0.85 | PLG (0.49) | PLA2G4APLGPLAU | |
| SCHEMBL9032982 | 0.85 | PLG (0.49) | PLA2G4APLGPLAU | |
| SCHEMBL9032967 | 0.85 | PLG (0.49) | PLA2G4APLGPLAU | |
| SCHEMBL9035312 | 0.85 | PLG (0.49) | PLA2G4APLGPLAU | |
| SCHEMBL845981 | 0.84 | PLG (0.53) | PLA2G4APLGPLAU | |
| SCHEMBL3351795 | 0.83 | MCL1 (0.61) | PLA2G4AHCAR3MCL1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-B1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-12-11 | — | — | EP | disclosed |
| US-6265536-B1 | MICROBIOCIDE AND FUNGICIDE WHICH IS INHIBITOR OF BETA-1,3-GLUCAN SYNTHASE; TREATMENT OF PNEUMOCYSTIS CARINII INFECTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6107458-A | FUNGICIDE WHICH IS BETA-1,3-GLYCAN SYNTHASE INHIBITOR; FOR PROPHYLAXIS AND TREATMENT OF PNEUMOCYSTIS CARINII INFECTIONS LIKE PNEUMONIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-22 | — | — | US | disclosed |
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996011210-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-18 | — | — | WO | disclosed |