Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 16/20 | 0.65 |
| ▸ | MMP1 | P03956 | 5/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335328 | 0.90 | MMP3 (0.55) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7341297 | 0.90 | MMP3 (0.62) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7343881 | 0.89 | CA1 (0.53) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7337236 | 0.89 | MMP3 (0.58) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7345078 | 0.88 | MMP3 (0.65) | MMP3MMP1MMP2KDM4EALDH1A1 | |
| SCHEMBL7333431 | 0.88 | MMP3 (0.57) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7342416 | 0.88 | MMP3 (0.66) | MMP3MMP1MMP2KDM4EALDH1A1 | |
| SCHEMBL7333422 | 0.87 | MMP3 (0.61) | MMP3MMP1KDM4EALDH1A1APOBEC3G | |
| SCHEMBL7336654 | 0.87 | MMP3 (0.65) | MMP3MMP1MMP2KDM4EALDH1A1 | |
| SCHEMBL7339940 | 0.86 | MMP3 (0.61) | MMP3MMP1MMP2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847148-A | Thiadiazole derivatives useful for the treatment of diseases related to connective tissue degradation | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-08 | — | — | US | disclosed |