Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 17/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.65 |
| ▸ | PDE4A | P27815 | 6/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.65 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340497 | 1.00 | PDE4B (0.65) | PDE4BPDE4DPDE4APDE4CCYP2B6 | |
| SCHEMBL7352724 | 0.86 | PDE4B (0.73) | PDE4BPDE4DPDE4APDE4CCYP2B6 | |
| SCHEMBL7359780 | 0.86 | PDE4B (0.76) | PDE4BPDE4DPDE4APDE4CCYP2B6 | |
| SCHEMBL7361164 | 0.81 | PDE4B (0.66) | PDE4BPDE4DPDE4APDE4CCYP2B6 | |
| SCHEMBL985307 | 0.81 | PDE4B (0.82) | PDE4BPDE4DPDE4APDE4CCYP2B6 | |
| SCHEMBL15270505 | 0.80 | PDE4D (1.00) | PDE4BPDE4DPDE4APDE4CCYP2B6 | |
| SCHEMBL7353387 | 0.80 | PDE4B (0.63) | PDE4BPDE4DPDE4APDE4CCYP2B6 | |
| Piclamilast SCHEMBL26573 | 0.79 | PDE4D (1.00) | PDE4BPDE4DPDE4APDE4CCYP2B6 | |
| SCHEMBL7355308 | 0.79 | PDE4D (0.73) | PDE4BPDE4DPDE4APDE4CCYP2B6 | |
| SCHEMBL6878175 | 0.79 | PDE4B (0.85) | PDE4BPDE4DPDE4APDE4CCYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031476-A1 | AROMATIC HYDROXYETHERS | RHONE-POULENC RORER LIMITED (GB) | 1996-10-10 | — | — | WO | disclosed |