Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 16/20 | 1.00 |
| ▸ | PDE4A | P27815 | 10/20 | 1.00 |
| ▸ | PDE4B | Q07343 | 10/20 | 1.00 |
| ▸ | PDE4C | Q08493 | 10/20 | 1.00 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.61 |
| ▸ | PDE5A | O76074 | 3/20 | 0.60 |
| ▸ | PDE1A | P54750 | 2/20 | 0.60 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.60 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335911 | 0.99 | PDE4D (0.98) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL14456041 | 0.94 | PDE4D (0.88) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL7359687 | 0.93 | PDE4D (0.86) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL7341113 | 0.92 | PDE4D (0.84) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL7336534 | 0.92 | PDE4D (0.84) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL7336538 | 0.92 | PDE4D (0.84) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL7354173 | 0.91 | PDE4D (0.83) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| Piclamilast SCHEMBL2723503 | 0.90 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL70770 | 0.89 | PDE4D (0.80) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL7338641 | 0.89 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4333 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4704983-A2 | TREATMENT OF MEMORY LOSS WITH PHOSPHODIESTERASE INHIBITORS | Cyrano Therapeutics, Inc. (US) | 2026-03-11 | — | — | EP | claimed |
| US-20260041690-A1 | Treatment of Memory Loss with Phosphodiesterase Inhibitors | CYRANO THERAPEUTICS INC (US) | 2026-02-12 | — | — | US | claimed |
| EP-4565302-A1 | DRY POWDER INHALER | Chiesi Farmaceutici S.p.A. (IT) | 2025-06-11 | — | — | EP | claimed |
| EP-4561649-A1 | DRUG-COATED MEDICAL DEVICES AND METHODS OF MAKING | Bard Peripheral Vascular, Inc. (US) | 2025-06-04 | — | — | EP | claimed |
| US-12280057-B2 | Vasoactive topical compound to affect tissue blood flow, reduce tissue necrosis and promote healing | SOUTH DAKOTA BOARD OF REGENTS (US) | 2025-04-22 | — | — | US | claimed |
| US-20250049770-A1 | Phosphodiesterase 4 Inhibitor Decreases Thrombosis in Simulated ECMO Model | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2025-02-13 | — | — | US | claimed |
| WO-2025023975-A1 | METHODS FOR THE PREPARATION OF PHOSPHOLIPID BILAYER CARRIERS | BARD PERIPHERAL VASCULAR, INC. (US) | 2025-01-30 | — | — | WO | claimed |
| US-20250017878-A1 | USE OF NADOLOL TO TREAT CHRONIC OBSTRUCTIVE PULMONARY DISEASE BY BLOCKAGE OF THE ARRESTIN-2 PATHWAY | CHRONIC AIRWAY THERAPEUTICS LTD (AU) | 2025-01-16 | — | — | US | claimed |
| WO-2024242668-A1 | PROTECTIVE COVERINGS FOR DRUG COATED BALLOONS | BARD PERIPHERAL VASCULAR, INC. (US) | 2024-11-28 | — | — | WO | claimed |
| US-20240366586-A1 | METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-11-07 | — | — | US | claimed |
| US-5908639-A | DRUG AND ANTISTATIC AGENT | RHONE-POULENC RORER LIMITED (GB) | 1999-06-01 | — | — | US | claimed |
| EP-0904266-A1 | NITROSATED AND NITROSYLATED COMPOUNDS AND COMPOSITIONS AND THEIR USE FOR TREATING RESPIRATORY DISORDERS | Nitromed, Inc. (US) | 1999-03-31 | — | — | EP | claimed |
| WO-1997034871-A1 | NITROSATED AND NITROSYLATED COMPOUNDS AND COMPOSITIONS AND THEIR USE FOR TREATING RESPIRATORY DISORDERS | NITROMED, INC. (US) | 1997-09-25 | — | — | WO | claimed |
| EP-0654991-B1 | INHALATION POWDER CONTAINING ANTISTATIC AGENT | RHONE POULENC RORER LTD (GB) | 1997-06-11 | — | — | EP | claimed |
| EP-0497564-B1 | Benzamides | RHONE POULENC RORER LTD (GB) | 1995-12-27 | — | — | EP | claimed |
| EP-0654991-A1 | INHALATION POWDER CONTAINING ANTISTATIC AGENT. | RHONE POULENC RORER LTD (GB) | 1995-05-31 | — | — | EP | claimed |
| US-5340827-A | Phenylcarboxamide compounds which have useful pharmaceutical activity | CELLTECH, LIMITED (GB) | 1994-08-23 | — | — | US | claimed |
| EP-0607373-A1 | TRISUBSTITUTED PHENYL DERIVATIVES AS SELECTIVE PHOSPHODIESTERASE IV INHIBITORS. | CELLTECH LTD (GB) | 1994-07-27 | — | — | EP | claimed |
| WO-1994004133-A1 | INHALATION POWDER CONTAINING ANTISTATIC AGENT | RHONE-POULENC RORER LIMITED (GB) | 1994-03-03 | — | — | WO | claimed |
| WO-1993025517-A1 | TRISUBSTITUTED PHENYL DERIVATIVES AS SELECTIVE PHOSPHODIESTERASE IV INHIBITORS | CELLTECH LIMITED (GB) | 1993-12-23 | — | — | WO | claimed |