Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 15/20 | 0.69 |
| ▸ | EDNRB | P24530 | 11/20 | 0.69 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789252 | 0.93 | EDNRA (0.79) | EDNRAEDNRBAGTR1 | |
| SCHEMBL7339468 | 0.87 | EDNRA (0.84) | EDNRAEDNRBAGTR1 | |
| SCHEMBL7331230 | 0.82 | EDNRA (0.83) | EDNRAEDNRBAGTR1 | |
| L-754142 SCHEMBL29551244 | 0.81 | EDNRA (1.00) | EDNRAEDNRBAGTR1 | |
| L-754142 SCHEMBL4193035 | 0.81 | EDNRA (1.00) | EDNRAEDNRBAGTR1 | |
| L-754142 SCHEMBL7722258 | 0.81 | EDNRA (0.98) | EDNRAEDNRBAGTR1 | |
| L-754142 SCHEMBL4202655 | 0.81 | EDNRA (0.98) | EDNRAEDNRBAGTR1 | |
| SCHEMBL2561123 | 0.80 | EDNRA (0.73) | EDNRAEDNRBAGTR1 | |
| SCHEMBL25013425 | 0.79 | EDNRA (0.70) | EDNRAEDNRBAGTR1 | |
| SCHEMBL7397394 | 0.78 | EDNRA (0.62) | EDNRAEDNRBAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774965-A4 | PHENOXYPHENYLACETIC ACID DERIVATIVES | MERCK & CO INC (US) | 1997-10-29 | — | — | EP | disclosed |
| EP-0774965-A1 | PHENOXYPHENYLACETIC ACID DERIVATIVES | MERCK & CO. INC. (US) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004905-A1 | PHENOXYPHENYLACETIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1996-02-22 | — | — | WO | disclosed |