Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 12/20 | 0.62 |
| ▸ | EDNRB | P24530 | 9/20 | 0.62 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339367 | 0.89 | EDNRA (0.75) | EDNRAEDNRBAGTR1 | |
| SCHEMBL8789252 | 0.85 | EDNRA (0.79) | EDNRAEDNRBAGTR1 | |
| SCHEMBL7340680 | 0.78 | EDNRA (0.69) | EDNRAEDNRBAGTR1 | |
| SCHEMBL8124977 | 0.78 | EDNRA (0.81) | EDNRAEDNRBAGTR1 | |
| SCHEMBL7334516 | 0.77 | EDNRA (0.58) | EDNRAEDNRBAGTR1 | |
| SCHEMBL29525200 | 0.76 | EDNRA (1.00) | EDNRAEDNRBAGTR1 | |
| SCHEMBL8904132 | 0.76 | EDNRA (0.78) | EDNRAEDNRBAGTR1 | |
| SCHEMBL795556 | 0.76 | EDNRA (0.79) | EDNRAEDNRBAGTR1 | |
| SCHEMBL8903408 | 0.76 | EDNRA (0.81) | EDNRAEDNRBAGTR1 | |
| SCHEMBL7331230 | 0.76 | EDNRA (0.83) | EDNRAEDNRBAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004905-A1 | PHENOXYPHENYLACETIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1996-02-22 | — | — | WO | disclosed |