Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL770728 | 0.87 | PRMT1 (0.58) | PRMT1TSHRLMNANFKB1PMP22 | |
| SCHEMBL17760456 | 0.87 | PRMT1 (0.58) | PRMT1TSHRLMNANFKB1PMP22 | |
| SCHEMBL7002091 | 0.87 | PRMT1 (0.58) | PRMT1TSHRLMNANFKB1PMP22 | |
| SCHEMBL26904254 | 0.87 | PRMT1 (0.58) | PRMT1TSHRLMNANFKB1PMP22 | |
| SCHEMBL1400994 | 0.85 | LMNA (0.55) | PRMT1TSHRLMNANFKB1PMP22 | |
| SCHEMBL1401106 | 0.81 | — | — | |
| SCHEMBL25409488 | 0.80 | TSHR (0.67) | PRMT1TSHRLMNANFKB1PMP22 | |
| SCHEMBL10596725 | 0.80 | TSHR (0.67) | PRMT1TSHRLMNANFKB1PMP22 | |
| SCHEMBL16713412 | 0.80 | TSHR (0.67) | PRMT1TSHRLMNANFKB1PMP22 | |
| SCHEMBL19643017 | 0.80 | TSHR (0.67) | PRMT1TSHRLMNANFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4639468-A | Derivatives of glycinamide, their preparation and their use | CONTINENTAL PHARMA INC. (BE) | 1987-01-27 | — | — | US | disclosed |