Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339143 | 0.87 | RXFP1 (0.48) | F10PRSS1HTTL3MBTL1MEN1 | |
| SCHEMBL23489334 | 0.86 | F10 (0.51) | F10PRSS1HTTL3MBTL1MEN1 | |
| SCHEMBL7343748 | 0.85 | MEN1 (0.46) | F10PRSS1HTTL3MBTL1MEN1 | |
| SCHEMBL6773153 | 0.84 | ITGB3 (0.55) | F10PRSS1HTTL3MBTL1MEN1 | |
| SCHEMBL7343738 | 0.84 | PLK4 (0.47) | F10PRSS1HTTL3MBTL1MEN1 | |
| SCHEMBL7372871 | 0.84 | PLK4 (0.50) | MEN1KMT2ARXFP1GAAPLK4 | |
| SCHEMBL6366986 | 0.84 | PLA2G10 (0.47) | HTTL3MBTL1MEN1KMT2AITGB3 | |
| SCHEMBL7840867 | 0.83 | ITGB3 (0.46) | F10PRSS1HTTL3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL6773326 | 0.83 | PLA2G10 (0.46) | HTTL3MBTL1MEN1KMT2AITGB3 | |
| Hydrochloric Acid SCHEMBL6368863 | 0.83 | PLA2G10 (0.46) | HTTL3MBTL1MEN1KMT2AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |