Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340974 | 1.00 | CYP1A2 (0.43) | CYP1A2CYP2D6ALOX15CYP2C19SLC1A3 | |
| SCHEMBL7864760 | 1.00 | CYP1A2 (0.43) | CYP1A2CYP2D6ALOX15CYP2C19SLC1A3 | |
| SCHEMBL21132261 | 0.86 | CYP2D6 (0.46) | CYP1A2CYP2D6ALOX15CYP2C19SLC1A3 | |
| SCHEMBL31439838 | 0.83 | EPHX2 (0.36) | KDM4EEPHX2 | |
| SCHEMBL7311712 | 0.83 | EPHX2 (0.36) | KDM4EEPHX2 | |
| SCHEMBL949192 | 0.83 | EPHX2 (0.36) | KDM4EEPHX2 | |
| Hydrochloric Acid SCHEMBL949191 | 0.81 | EPHX2 (0.35) | KDM4EEPHX2 | |
| Hydrochloric Acid SCHEMBL7316491 | 0.81 | EPHX2 (0.35) | KDM4EEPHX2 | |
| Hydrochloric Acid SCHEMBL949189 | 0.81 | EPHX2 (0.35) | KDM4EEPHX2 | |
| Hydrochloric Acid SCHEMBL949193 | 0.81 | EPHX2 (0.35) | KDM4EEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10443026-B2 | Polygonal scaffold and manufacturing method thereof, and protein modulator and manufacturing method thereof | NATIONAL TSING HUA UNIVERSITY (TW) | 2019-10-15 | — | — | US | disclosed |
| US-20190194590-A1 | POLYGONAL SCAFFOLD AND MANUFACTURING METHOD THEREOF, AND PROTEIN MODULATOR AND MANUFACTURING METHOD THEREOF | NATIONAL TSING HUA UNIVERSITY (TW) | 2019-06-27 | — | — | US | disclosed |
| US-4316906-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194590-A1 | POLYGONAL SCAFFOLD AND MANUFACTURING METHOD THEREOF, AND PROTEIN MODULATOR AND MANUFACTURING METHOD THEREOF | PPIA, PPIH, FKBP1A | CYP1A2 3805/4885CYP2D6 4137/4885ALOX15 4383/4885 |
| US-10443026-B2 | Polygonal scaffold and manufacturing method thereof, and protein modulator and manufacturing method thereof | PPIA, PPIH, FKBP1A | CYP1A2 4091/4885CYP2D6 4295/4885ALOX15 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.