Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.73 |
| ▸ | CTSL | P07711 | 10/20 | 0.73 |
| ▸ | CTSS | P25774 | 8/20 | 0.73 |
| ▸ | CTSB | P07858 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27474580 | 1.00 | CTSK (0.73) | CTSKCTSLCTSSCTSB | |
| SCHEMBL27472847 | 0.95 | CTSK (0.73) | CTSKCTSLCTSSCTSB | |
| SCHEMBL27472846 | 0.95 | CTSK (0.73) | CTSKCTSLCTSSCTSB | |
| SCHEMBL27472818 | 0.94 | CTSK (0.66) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7337143 | 0.94 | CTSK (0.66) | CTSKCTSLCTSSCTSB | |
| Hydrochloric Acid SCHEMBL27556174 | 0.94 | CTSK (0.75) | CTSKCTSLCTSSCTSB | |
| Hydrochloric Acid SCHEMBL27556172 | 0.94 | CTSK (0.75) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7377985 | 0.91 | CTSK (0.61) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7664197 | 0.86 | CTSK (0.73) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7372135 | 0.85 | CTSK (0.67) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804180-A4 | METHOD OF INHIBITING CATHEPSIN K | SMITHKLINE BEECHAM CORP (US) | 2001-09-05 | — | — | EP | claimed |
| EP-0804180-A1 | METHOD OF INHIBITING CATHEPSIN K | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-05 | — | — | EP | claimed |
| WO-1997016177-A9 | METHOD OF INHIBITING CATHEPSIN K | — | 1997-07-24 | — | — | WO | claimed |
| WO-1997016177-A1 | METHOD OF INHIBITING CATHEPSIN K | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | claimed |
| EP-0804180-A4 | METHOD OF INHIBITING CATHEPSIN K | SMITHKLINE BEECHAM CORP (US) | 2001-09-05 | — | — | EP | disclosed |
| CN-1177293-A | Method for inhibiting cathepsin K | SMITHKLINE BEECHAM CORP (US) | 1998-03-25 | — | — | CN | disclosed |
| EP-0804180-A1 | METHOD OF INHIBITING CATHEPSIN K | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1997016177-A9 | METHOD OF INHIBITING CATHEPSIN K | — | 1997-07-24 | — | — | WO | disclosed |
| WO-1997016177-A1 | METHOD OF INHIBITING CATHEPSIN K | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | disclosed |